Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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47
Tocris Bioscience™ N-Acetylcysteine amide
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Glutathione (GSH) precursor; neuroprotective
| Target | Additional Antioxidant Compounds |
|---|---|
| CAS | 38520-57-9 |
| Chemical Name or Material | (2R)-2-(Acetylamino)-3-mercaptopropanamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C5H10N2O2S |
| Formula Weight | 162.21 |
48
Tocris Bioscience™ Hydroxychloroquine sulfate
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Autophagy inhibitor; also TLR9 inhibitor
| Target | Autophagy-related Compounds |
|---|---|
| CAS | 747-36-4 |
| Purity | >99% |
| Chemical Name or Material | 2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol sulfate |
| Recommended Storage | Store at 4°C |
| Molecular Formula | C18H28ClN3O5S |
| Formula Weight | 433.95 |
49
| CAS | 3734-33-6 |
|---|---|
| Synonym | unii-m5ba6gaf1o |
| Molecular Formula | C28H34N2O3 |
51
Tocris Bioscience™ HBC 530
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GFP fluorophore mimic for imaging RNA in live cells; activated by binding to Pepper aptamers; suitable for confocal and two-photon microscopy
52
Tocris Bioscience™ Polyamine Supplement x1000 (lyophilized)
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Media supplement to boost cell growth; used as component of CEPT cocktail to enhance stem cell viability
53
Tocris Bioscience™ Thalidomide 4'-oxyacetamide-alkylC6-amine
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Thalidomide-alkylC6-amine
54
Tocris Bioscience™ NG 25
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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TGF-β-activated kinase (TAK1) inhibitor
55
Tocris Bioscience™ Telenzepine dihydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 147416-96-4 Molecular Formula: C19H24Cl2N4O2S
| CAS | 147416-96-4 |
|---|---|
| Molecular Formula | C19H24Cl2N4O2S |
56
Tocris Bioscience™ L-733,060 hydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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CAS: 148687-76-7 Molecular Formula: C20H20ClF6NO
| CAS | 148687-76-7 |
|---|---|
| Molecular Formula | C20H20ClF6NO |
57
Tocris Bioscience™ BAY 58-2667 hydrochloride
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent soluble guanylyl cyclase (sGC) activator
58
Tocris Bioscience™ JBJ-03-142-02
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Highly potent EGFR and ErbB2 inhibitor; inhibts wild type and mutated receptors
59
Tocris Bioscience™ PND 1186
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Potent FAK inhibitor; orally bioavailable
| Product Type | Inhibitor |
|---|---|
| Purity | 98% |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C25H26F3N5O3 |
| Formula Weight | 501.51 |
60
Tocris Bioscience™ CL 82198 hydrochloride
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CAS: 1188890-36-9 Molecular Formula: C17H23ClN2O3
| CAS | 1188890-36-9 |
|---|---|
| Molecular Formula | C17H23ClN2O3 |